{"id":463,"date":"2015-08-26T16:33:05","date_gmt":"2015-08-26T07:33:05","guid":{"rendered":"https:\/\/juntan.net\/newblog\/index.php\/2015\/08\/26\/post_366\/"},"modified":"2022-10-31T20:21:09","modified_gmt":"2022-10-31T11:21:09","slug":"post_366","status":"publish","type":"post","link":"https:\/\/juntan.net\/blog\/kidney-disease\/post_366\/","title":{"rendered":"\u814e\u81d3\u75c5\u3068\u8178\u5185\u74b0\u5883 ~\u597d\u5faa\u74b0\u3068\u60aa\u5faa\u74b0~"},"content":{"rendered":"

\u7686\u69d8\u3053\u3093\u306b\u3061\u306f\uff01
\n\u6c34\u66dc\u62c5\u5f53\u30b9\u30bf\u30c3\u30d5M\u5b50\u3067\u3059\"happy01\"<\/p>\n

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\n\u4eca\u6708\u306f-8\uff5e-11kg\u306e\u3042\u305f\u308a\u3092\u3055\u307e\u3088\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u306e1\u9031\u9593\u306f-10kg\u5468\u8fba\u3092\u30a6\u30ed\u30a6\u30ed\u2026\u7f8e\u5473\u3057\u304f\u7cd6\u8cea\u3092\u6442\u308a\u3064\u3064\uff0c\u6b69\u3044\u305f\u308a\u5730\u9053\u306b\u904b\u52d5\u3057\u3088\u3046\u2026\u3068\u601d\u3063\u3066\u304a\u308a\u307e\u3059\"think\"<\/p>\n

\u3055\u3066\uff0c\u672c\u65e5\u306f\u5b9f\u9a13\u306e\u5408\u9593\u306b\u3061\u307e\u3061\u307e\u8aad\u3093\u3067\u3044\u305f\u6587\u732e\u3092\u3054\u7d39\u4ecb\uff5e\u2026\u6587\u5b57\u3070\u3063\u304b\u308a\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u304c\u3088\u308d\u3057\u3051\u308c\u3070\u3054\u4e00\u8aad\u304f\u3060\u3055\u3044\"coldsweats01\"<\/p>\n

\u4eca\u5e74\u306e4\u6708\u306b\u300cNephrology Dialysis Transplantation\uff08\u814e\u81d3\u5b66\u3068\u900f\u6790\u3068\u79fb\u690d\uff09\u300d\u3068\u3044\u3046\u8ad6\u6587\u96d1\u8a8c\u306b\u304a\u3044\u3066\uff0c\u300c\u6162\u6027\u814e\u4e0d\u5168\u306b\u304a\u3051\u308b\u8178\u5185\u7d30\u83cc\u53e2\u306e\u5909\u5316\u3068\u4e0a\u76ae\u30d0\u30ea\u30a2\u306e\u69cb\u9020\u30fb\u6a5f\u80fd\u306e\u640d\u5931\uff1b\u305d\u306e\u672c\u8cea\uff0c\u30e1\u30ab\u30cb\u30ba\u30e0\uff0c\u7d50\u679c\u3068\u6709\u7528\u306a\u6cbb\u7642\u6cd5\u300d\u3068\u984c\u3057\u305f\u30ec\u30d3\u30e5\u30fc\u304c\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment<\/p>\n

Nephrol Dial Transplant (2015) 0; 1-10
\nNosratola D. et.al<\/p>\n

\u8178\u5185\u7d30\u83cc\u304c\u4f5c\u308b\u814e\u81d3\u306a\u3069\u306e\u5185\u81d3\u306b\u8ca0\u62c5\u3092\u304b\u3051\u308b\u7269\u8cea\uff08\u5c3f\u6bd2\u6027\u7269\u8cea\uff1b\u30a4\u30f3\u30c9\u30fc\u30eb\uff0cp-\u30af\u30ec\u30be\u30fc\u30eb\uff0c\u30c8\u30ea\u30e1\u30c1\u30eb\u30a2\u30df\u30f3\u7b49\uff09\u306e\u5b58\u5728\u306f\u65e2\u306b\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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1\uff0c\u5c3f\u7d20\u3084\u4ed6\u306e\u5c3f\u6bd2\u6027\u7269\u8cea\u3092\u6e1b\u3089\u3059\u6226\u7565
\n2\uff0c\u9ad8\u7e4a\u7dad\u6804\u990a
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\n\u00a04\uff0c\u7d4c\u53e3\u5438\u7740\u5264<\/strong><\/span>
\n5\uff0c\u8178\u7ba1\u306e\u6d6e\u816b\u3092\u6700\u5c0f\u9650\u306b\u3057\uff0c\u8178\u7ba1\u306e\u865a\u8840\u3092\u9632\u3050\u76ee\u7684\u306e\u6226\u7565
\n6\uff0c\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9<\/p>\n

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\n2<\/strong>\u306f\u5584\u7389\u83cc\u306e\u30a8\u30b5\u3068\u306a\u308b\u98df\u7269\u7e4a\u7dad\u3092\u305f\u304f\u3055\u3093\u6442\u3063\u3066\uff0c\u5584\u7389\u83cc\u3092\u5897\u3084\u3057\uff0c\u5927\u8178\u306e\u4e0a\u76ae\u7d30\u80de\u3084\u514d\u75ab\u7cfb\u306eT\u5236\u5fa1\u30ea\u30f3\u30d1\u7403\u306e\u91cd\u8981\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u306b\u306a\u308b\u77ed\u9396\u8102\u80aa\u9178\u3092\u305f\u304f\u3055\u3093\u5408\u6210\u3057\u3066\u3082\u3089\u3063\u3066\uff0c\u8178\u3092\u3067\u304d\u308b\u3060\u3051\u5065\u5eb7\u306b\u3057\u3088\u3046\uff01\u3068\u3044\u3046\u65b9\u6cd5\u3067\u3059\u3002<\/p>\n

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\n\u8178\u5185\u7d30\u83cc\u3084\u8178\u5185\u74b0\u5883\u306b\u306f\u3044\u3044\u3053\u3068\u3060\u3051\u3069\uff0c\u304a\u8179\u304c\u5f35\u3063\u305f\u308a\u304a\u306a\u3089\u304c\u5897\u3048\u305f\u308a\u2026\u306f\u793e\u4f1a\u751f\u6d3b\u3092\u884c\u3046\u4e0a\u3067\u306f\u3061\u3087\u3063\u3068\u30de\u30a4\u30ca\u30b9\u9762\u304b\u306a\u3068\u601d\u3044\u307e\u3059\"coldsweats01\"<\/p>\n

3<\/strong>\u306f\u70ad\u6c34\u5316\u7269\uff08\u7cd6\u9396\uff09\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u672a\u6d88\u5316\u306e\u7cd6\u9396\u3092\u5927\u8178\u306b\u9001\u308a\uff0c\u3053\u308c\u307e\u305f\u5584\u7389\u83cc\u306e\u990c\u3068\u3057\u307e\u3057\u3087\u3046\u3068\u3044\u3046\u65b9\u6cd5\u3067\u3059\u3002
\n\u7cd6\u5c3f\u75c5\u306e\u304a\u85ac\u306e\u4e00\u3064\u3068\u3057\u3066\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u6d3b\u6027\u963b\u5bb3\u5264\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u304c\uff08\u30d6\u30c9\u30a6\u7cd6\u3078\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u7de9\u3084\u304b\u306b\u3059\u308b\uff09\uff0c2\u3068\u540c\u69d8\u306b\u8178\u5185\u3067\u306e\u767a\u9175\u306b\u3088\u308b\u5f0a\u5bb3\u3082\u3042\u308b\u3088\u3046\u3067\u3059\"think\"<\/p>\n

4<\/strong>\u306f\u7d4c\u53e3\u5438\u7740\u5264\uff0c\u7279\u306b\u300c\u6162\u6027\u814e\u4e0d\u5168\u306e\u9032\u884c\u6291\u5236\u85ac\u300d\u3067\u3042\u308b\u77f3\u6cb9\u30d4\u30c3\u30c1\u7531\u6765\u306e\u300c\u70ad<\/strong><\/ins>\u300d\uff08AST-120\uff1b\u30af\u30ec\u30e1\u30b8\u30f3\u00ae\uff09\u306b\u3064\u3044\u3066\u8a00\u53ca\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u8178\u7ba1\u5185\u3067\u98df\u4e8b\u7531\u6765\u3084\u8178\u5185\u7d30\u83cc\u7531\u6765\u306e\u5c3f\u6bd2\u6027\u7269\u8cea\u3092\u70ad\u306b\u5438\u7740\u3057\uff0c\u4fbf\u3068\u3057\u3066\u6392\u51fa\uff08\u8840\u7ba1\u306e\u4e2d\u306b\u5165\u308c\u305a\uff0c\u4ed6\u306e\u81d3\u5668\u306b\u79fb\u52d5\u3055\u305b\u306a\u3044\uff09\u3059\u308b\u3053\u3068\u3067\u8840\u4e2d\u306e\u30a4\u30f3\u30c9\u30ad\u30b7\u30eb\u786b\u9178\uff08\u30a4\u30f3\u30c9\u30fc\u30eb\u304c\u809d\u81d3\u3067\u4f5c\u308a\u5909\u3048\u3089\u308c\u305f\u7269\u8cea\uff09\u7b49\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3044\u3046\u304a\u85ac\u3067\u3059\u3002<\/p>\n

\u7d4c\u53e3\u5438\u7740\u70ad\uff08AST-120\uff09\u304c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u5168\u8eab\u6027\u708e\u75c7\u306e\u53cc\u65b9\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u306e\u3067\u3059\u304c\uff0c\u305d\u308c\u306f\u5c3f\u6bd2\u6027\u7269\u8cea\u306e\u5438\u7740\u9664\u53bb\u306e\u307b\u304b\u306b\uff0c\u30a2\u30f3\u30e2\u30cb\u30a2\u306e\u5438\u7740\u3092\u901a\u3058\u3066\u8178\u306e\u30d0\u30ea\u30a2\u69cb\u9020\u4fdd\u8b77\u306b\u3082\u50cd\u3044\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u898b\u89e3\u3067\uff0c\u7b46\u8005\u3089\u306f\u814e\u4e0d\u5168\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3053\u306e\u4eee\u8aac\u3092\u691c\u8a3c\u6e08\u307f\u3067\u3059\u3002
\n\u305d\u306e\u5b9f\u9a13\u3067\u306f\u8840\u4e2d\u306e\u7d30\u83cc\u6bd2\u7d20\uff0c\u5404\u7a2e\u708e\u75c7\u6027\u7269\u8cea\uff08\u8907\u6570\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\uff09\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u6307\u6a19\u7269\u8cea\u306e\u6fc3\u5ea6\u4f4e\u4e0b\u3082\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n

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5<\/strong>\u306f\u8178\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6b63\u5e38\u306b\u7dad\u6301\u3059\u308b\u305f\u3081\uff0c\u8178\u306e\u300c\u6d6e\u816b\u300d\u3084\u300c\u865a\u8840\u300d\u3092\u62db\u304b\u306a\u3044\u3088\u3046\u306b\uff0c\u4f7f\u7528\u3059\u308b\u533b\u85ac\u54c1\u3084\u900f\u6790\u65b9\u6cd5\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u3044\u3046\u3082\u306e\u3067\uff0c\u98df\u7269\u306e\u6c34\u5206\u91cf\u3084\u30ca\u30c8\u30ea\u30a6\u30e0\u306e\u6442\u53d6\u91cf\u306b\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3068\u306e\u3053\u3068\u3067\u3057\u305f\u3002<\/p>\n

6<\/strong>\u306f\u5c3f\u6bd2\u6027\u7269\u8cea\u3092\u5c11\u306a\u304f\u3059\u308b\u305f\u3081\u306b\u7d30\u83cc\u985e\u3092\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u624b\u6cd5\u306b\u3064\u3044\u3066\u3067\u3059\u304c\uff0c\u3053\u308c\u3089\u306e\u4e2d\u306b\u306f\u5c3f\u7d20\u6fc3\u5ea6\u3092\u4e0b\u3052\u3055\u305b\u308b\u305f\u3081\u306b\u5c3f\u7d20\u3092\u30a2\u30f3\u30e2\u30cb\u30a2\u306b\u5206\u89e3\u3059\u308b\u9175\u7d20\u3092\u6301\u3064\u7a2e\u985e\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\uff0c\u601d\u3046\u3088\u3046\u306a\u6210\u679c\u304c\u4e0a\u304c\u3089\u306a\u3044\u306e\u306f\u3053\u306e\u30a2\u30f3\u30e2\u30cb\u30a2\u3078\u306e\u5909\u63db\u304c\u5c3f\u7d20\u6fc3\u5ea6\u306f\u4e0b\u3052\u308b\u3051\u308c\u3069\u3082\u4e00\u65b9\u3067\u5c0f\u8178\u30d0\u30ea\u30a2\u6a5f\u80fd\u3078\u306e\u60aa\u5f71\u97ff\u3092\u751f\u3058\u3055\u305b\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u306e\u898b\u65b9\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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