{"id":12660,"date":"2021-11-01T17:00:13","date_gmt":"2021-11-01T08:00:13","guid":{"rendered":"https:\/\/juntan.net\/newblog\/index.php\/2021\/10\/29\/kiyoratuushin30\/"},"modified":"2024-07-25T16:32:22","modified_gmt":"2024-07-25T07:32:22","slug":"kiyoratuushin30","status":"publish","type":"post","link":"https:\/\/juntan.net\/blog\/letter\/kiyoratuushin30\/","title":{"rendered":"\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u306e\u627f\u8a8d\u3055\u308c\u305f&#8221;\u65b0\u85ac\u201d\u30d5\u30a9\u30b7\u30fc\u30ac\uff08SGLT2\u963b\u5bb3\u85ac\uff09\u306e\u6700\u65b0\u60c5\u5831\u3092\u304a\u5c4a\u3051\u3057\u307e\u3059"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p>\u98df\u3079\u308b\u7d14\u70ad\u304d\u3088\u3089\u901a\u4fe1vol.29\uff082021.11\u6708\u53f7\uff09<br><br>\u3044\u3064\u3082\u98df\u3079\u308b\u7d14\u70ad\u304d\u3088\u3089\u3092\u3054\u611b\u9867\u3044\u305f\u3060\u304d\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3059\u3002<br><br>\u304d\u3088\u3089\u901a\u4fe1\u62c5\u5f53\u306e\u3086\u3063\u304d\u30fc\u3067\u3059\uff01<br><br>\u4eca\u56de\u306f\u3053\u306e\u590f\u306b\u627f\u8a8d\u3055\u308c\u305f\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u6cbb\u7642\u85ac\u201c\u30d5\u30a9\u30b7\u30fc\u30ac\u201d\u306b\u3064\u3044\u3066\u306e\u6700\u65b0\u60c5\u5831\u3092\u304a\u5c4a\u3051\u3057\u307e\u3059\u3002<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u306b\u3064\u3044\u306b\u65b0\u85ac\u767b\u5834<\/h2>\n\n\n\n<p><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"300\" class=\"alignnone size-medium wp-image-12663\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/b522ed8c95f0a4dfeede08f7d3609682-450x300.jpg\" alt=\"\u85ac\u306e\u8aac\u660e\u3092\u3059\u308b\u533b\u5e2b\u3000\u7537\u6027\u533b\u5e2b\"><br>\u300e\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u306e\u6cbb\u7642\u85ac\u304c\u56fd\u5185\u521d\u306e\u627f\u8a8d\u300f\u3068\u5831\u9053\u3055\u308c\u305f\u306e\u306f\u8a18\u61b6\u306b\u65b0\u3057\u3044\u3068\u3053\u308d\u3067\u3059\u3002<br><br>\u814e\u81d3\u75c5\u306b\u306f\u85ac\u304c\u306a\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u7740\u5b9f\u306b\u7814\u7a76\u306f\u9032\u3093\u3067\u3044\u305f\u306e\u3067\u3059\uff01<br><br>\u4eca\u56de\u627f\u8a8d\u3055\u308c\u305f\u201c\u30d5\u30a9\u30b7\u30fc\u30ac\u201d \uff08\u4e00\u822c\u540d\uff1a\u30c0\u30d0\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\uff09\u3063\u3066\u4e00\u4f53\u3069\u3093\u306a\u85ac\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u30d5\u30a9\u30b7\u30fc\u30ac\u306e\u6b74\u53f2<\/h2>\n\n\n\n<p><img loading=\"lazy\" decoding=\"async\" width=\"270\" height=\"270\" class=\"alignnone size-full wp-image-12664\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/833d4072e663b64a68e5cc1b797f5233.jpg\" alt=\"SGLT2\u963b\u5bb3\u85ac\u3000\u30d5\u30a9\u30b7\u30fc\u30ac\u3000\u5546\u54c1\u753b\u50cf\"><br>\u65e5\u672c\u3067\u306f2014\u5e74\u306b2\u578b\u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u627f\u8a8d\u3055\u308c\u30012019\u5e74\u306b1\u578b\u7cd6\u5c3f\u75c5\u3001\u66f4\u306b\u306f2020\u5e74\u306b\u6162\u6027\u5fc3\u4e0d\u5168\u6cbb\u7642\u85ac\u3068\u3057\u3066\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<br><br>\u305d\u3057\u30662021\u5e748\u6708\u7cd6\u5c3f\u75c5\u306e\u6709\u7121\u306b\u95a2\u308f\u3089\u305a\u6162\u6027\u814e\u81d3\u75c5\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u3082\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<br><br>\uff08\u4f46\u3057\u3001\u672b\u671f\u814e\u4e0d\u5168\u307e\u305f\u306f\u900f\u6790\u65bd\u884c\u4e2d\u306e\u60a3\u8005\u306f\u9664\u304f\uff09<br><br>\u3061\u306a\u307f\u306b\u85ac\u4fa1\u306f10\u338e\uff081\u65e5\u5206\uff09\u3067274\u5186\u30013\u5272\u8ca0\u62c5\u3060\u30681\u304b\u6708\u30672500\u5186\u307b\u3069\u306e\u8cbb\u7528\u306b\u306a\u308a\u307e\u3059\u3002<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u30d5\u30a9\u30b7\u30fc\u30ac\u3063\u3066\u3069\u3093\u306a\u85ac\uff1f<\/h2>\n\n\n\n<p><img loading=\"lazy\" decoding=\"async\" width=\"270\" height=\"270\" class=\"alignnone size-full wp-image-12665\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/0f8f33d4c7ccca15a8dfc0628b693f08.jpg\" alt=\"\u30d5\u30a9\u30b7\u30fc\u30ac\u3000SGFT2\u963b\u5bb3\u85ac\u3000\u9320\u5264\u5546\u54c1\u753b\u50cf\"><br>\u3053\u306e\u85ac\u306f\u814e\u81d3\u306b\u3042\u308bSGLT2\uff08\u5c3f\u4e2d\u306b\u6368\u3066\u3089\u308c\u305f\u7cd6\u3092\u518d\u5438\u53ce\u3057\u3066\u8840\u6db2\u306b\u623b\u3059\u7269\u8cea\uff09\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u5c3f\u4e2d\u306b\u7cd6\u3092\u6368\u3066\u3066\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002<br><br>\u30d5\u30a9\u30b7\u30fc\u30ac\u306e\u3088\u3046\u306a\u50cd\u304d\u306e\u85ac\u3092\u7dcf\u79f0\u3057\u3066SGLT2\u963b\u5bb3\u85ac\u3068\u547c\u3093\u3067\u304a\u308a\u3001\u307b\u304b\u306b\u3082\u6570\u7a2e\u985e\u3042\u308a\u307e\u3059\u3002<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u627f\u8a8d\u306e\u305f\u3081\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30d5\u30a9\u30b7\u30fc\u30ac\u306e\u56fd\u969b\u7684\u306a\u81e8\u5e8a\u8a66\u9a13\uff08DAPA-CKD\uff09\u3067\u306f\u7cd6\u5c3f\u75c5\u306e\u6709\u7121\u3092\u554f\u308f\u306a\u30444,304\u4f8b\u306e\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<br><br>\u9078\u3070\u308c\u305f\u306e\u306f\u6162\u6027\u814e\u81d3\u75c5\u306e\u30b9\u30c6\u30fc\u30b82\uff5e4\uff08eGFR\u304c75\uff5e25\uff09\u3001\u5c3f\u86cb\u767d\u304c\u51fa\u3066\u304a\u308a\u3001\u964d\u5727\u5264\uff08ARB\u307e\u305f\u306fACEI\uff09\u3092\u670d\u7528\u306e\u4eba\u3067\u3059\u3002<br><br>\u5bfe\u8c61\u8005\u3092\u534a\u5206\u305a\u3064\u306b\u5206\u3051\u3066\u3001\u30d5\u30a9\u30b7\u30fc\u30ac\u3092\u98f2\u307e\u306a\u304b\u3063\u305f\u30b0\u30eb\u30fc\u30d7\u30681\u65e51\u56de\u30d5\u30a9\u30b7\u30fc\u30ac10\u338e\u98f2\u3093\u3067\u3082\u3089\u3063\u305f\u30b0\u30eb\u30fc\u30d7\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<br><\/p>\n\n\n\n<figure class=\"wp-block-image is-resized\"><img decoding=\"async\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/29080a20e624bb9dd198821c3039c670-450x141.jpg\" alt=\"\u30d5\u30a9\u30b7\u30fc\u30ac\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\" class=\"wp-image-12666\" style=\"width:835px;height:262px\"\/><figcaption class=\"wp-element-caption\">SGLT2\u963b\u5bb3\u85ac\u306b\u3088\u308b\u814e\u4fdd\u8b77\u52b9\u679c<\/figcaption><\/figure>\n\n\n\n<p><br>\u30d5\u30a9\u30b7\u30fc\u30ac\u3092\u98f2\u3093\u3067\u3044\u305f\u30b0\u30eb\u30fc\u30d7\u306f<br>\u2460\u814e\u6a5f\u80fd\u306e\u60aa\u5316<br>\u2461\u672b\u671f\u814e\u4e0d\u5168\u3078\u306e\u9032\u884c<br>\u2462\u5fc3\u8840\u7ba1\u6b7b\u307e\u305f\u306f\u814e\u4e0d\u5168\u3067\u306e\u6b7b\u4ea1<br>\u2460\uff5e\u2462\u306e\u3044\u305a\u308c\u304b\u3078\u79fb\u884c\u3059\u308b\u30ea\u30b9\u30af\u304c39\uff05\u4f4e\u304b\u3063\u305f\u3068\u3044\u3046\u7d50\u679c\u304c\u3067\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u814e\u81d3\u75c5\u306e\u539f\u56e0\u304c\u9055\u3063\u3066\u3082\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b<\/h2>\n\n\n\n<p><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"300\" class=\"alignnone size-medium wp-image-12667\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/2bdddf1bd6d6fbd53c285bb59c37b99b-450x300.jpg\" alt=\"\u81e8\u5e8a\u8a66\u9a13\u3000\u5973\u533b\u3000\u533b\u5e2b\u3000\u8a66\u9a13\"><br>2019\u5e74\u306e\u900f\u6790\u5c0e\u5165\u60a3\u8005\u306e\u539f\u75be\u60a3\u306f\u4ee5\u4e0b\u306e\u9806\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>1\u4f4d\uff1a\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7<\/td><td>41.6%<\/td><\/tr><tr><td>2\u4f4d\uff1a\u9ad8\u8840\u5727\u304c\u539f\u56e0\u306e\u814e\u786c\u5316\u75c7<\/td><td>16.4%<\/td><\/tr><tr><td>3\u4f4d\uff1a\u7cf8\u7403\u4f53\u814e\u708e<\/td><td>14.9%<\/td><\/tr><tr><td>4\u4f4d\uff1a\u539f\u56e0\u4e0d\u660e<\/td><td>13.9%<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">\u900f\u6790\u5c0e\u5165\u8005\u306e\u814e\u6a5f\u80fd\u60aa\u5316\u306e\u539f\u56e0<\/figcaption><\/figure>\n\n\n\n<p>\u5168\u900f\u6790\u5c0e\u5165\u60a3\u8005\u306e86.8%\u304c1\uff5e4\u4f4d\u306e\u3044\u305a\u308c\u304b\u304c\u539f\u56e0\u3067\u3059\u3002<br><br>\u5b09\u3057\u3044\u3053\u3068\u306b\u30d5\u30a9\u30b7\u30fc\u30ac\u306f1\uff5e4\u4f4d\u3059\u3079\u3066\u306e\u30bf\u30a4\u30d7\u306e\u6162\u6027\u814e\u81d3\u75c5\u3067\u3082\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4eca\u56de\u306e\u627f\u8a8d\u53d6\u5f97\u3067\u4f55\u304c\u5909\u308f\u308b\u306e\uff1f<\/h2>\n\n\n\n<p><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"300\" class=\"alignnone size-medium wp-image-12595\" src=\"https:\/\/juntan.net\/blog\/wp-content\/uploads\/2021\/09\/400f7b122c01fb1ce0d562f267ff591b-450x300.jpg\" alt=\"\u7591\u554f\u3000\u8003\u3048\u308b\u5973\u6027\"><br>\u6b27\u7c73\u8af8\u56fd\u3067\u306f\u3001\u4e00\u8db3\u65e9\u304f\u6162\u6027\u814e\u81d3\u75c5\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u52b9\u80fd\u52b9\u679c\u304c\u8ffd\u52a0\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<br><br>\u3057\u304b\u3057\u65e5\u672c\u3067\u306f\u3001\u7cd6\u5c3f\u75c5\u3084\u5fc3\u4e0d\u5168\u304c\u306a\u3051\u308c\u3070\u30d5\u30a9\u30b7\u30fc\u30ac\u306f\u4f7f\u7528\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<br><br>\u4eca\u56de\u306e\u627f\u8a8d\u306b\u3088\u3063\u3066\u65e5\u672c\u56fd\u5185\u3067\u3082\u7cd6\u5c3f\u75c5\u3084\u5fc3\u4e0d\u5168\u306b\u95a2\u4fc2\u306a\u304f\u3001\u814e\u81d3\u75c5\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u3066\u4fdd\u967a\u9069\u5fdc\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<br><\/p>\n\n\n\n<h2 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alt=\"\u9078\u629e\u80a2\u3000\u8ff7\u3046\u5973\u6027\"><br>\u30d5\u30a9\u30b7\u30fc\u30ac\u6dfb\u4ed8\u6587\u7ae0\u306e\u300c\u52b9\u80fd\u53c8\u306f\u52b9\u679c\u300d\u306b\u6162\u6027\u814e\u81d3\u75c5\u304c\u8ffd\u52a0\u3055\u308c\u3001\u7cd6\u5c3f\u75c5\u306e\u6709\u7121\u306b\u95a2\u4fc2\u306a\u304f\u3001eGFR\u304c25\u4ee5\u4e0a\u3042\u308c\u3070\u57fa\u672c\u7684\u306b\u51e6\u65b9\u306e\u5bfe\u8c61\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002<br><br>\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u300e\u305f\u3060\u3057\u672b\u671f\u814e\u4e0d\u5168\u53c8\u306f\u900f\u6790\u65bd\u884c\u4e2d\u306e\u60a3\u8005\u3092\u9664\u304f\u300f\u3068\u3082\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u306e\u3067eGFR\u304c25\u672a\u6e80\u306e\u5834\u5408\u306f\u3001\u30ea\u30b9\u30af\u3068\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\uff08\u6069\u6075\uff09\u306b\u95a2\u3057\u3066\u533b\u5e2b\u3068\u306e\u5354\u8b70\u304c\u5fc5\u8981\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002<br><br>\u307e\u305f\u3001\u7cd6\u5c3f\u75c5\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u5834\u5408\u3082\u533b\u5e2b\u306b\u76f8\u8ac7\u304c\u5fc5\u8981\u3067\u3059\u3002<br><\/p>\n\n\n\n<h2 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